AN ATYPICAL SCF-LIKE UBIQUITIN LIGASE COMPLEX PROMOTES WALLERIAN DEGENERATION THROUGH REGULATION OF AXONAL NMNAT2

An Atypical SCF-like Ubiquitin Ligase Complex Promotes Wallerian Degeneration through Regulation of Axonal Nmnat2

Axon degeneration is a tightly regulated, self-destructive program that is a critical feature of many neurodegenerative diseases, but the molecular mechanisms regulating this program remain poorly understood.Here, we identify S-phase kinase-associated protein 1A (Skp1a), a core component of a Skp/Cullin/F-box (SCF)-type E3 ubiquitin ligase complex,

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PROTECTION ORDER VERSUS (?) PARENTAL AUTHORITY

Parental authority includes in its scope important decisions related to minors, as identified by Article 36 of Law no.272/2004 (form of education and professional training, complex medical treatments and surgery, residence of the child or administration of property), which are by consequence to be taken only by agreement of both parents.It is mybou

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BIO-SECURE BUBBLE AMID COVID-19 PANDEMIC: PESTEL ANALYSIS

Physical distancing was recommended to break the chain of transmission, with 761402,282 confirmed cases worldwide.The Bio-secure bubble system consisted of routine COVID-19 testing and cleaning of tournament locations.PESTEL analysis is a technique for examining external macro-environmental variables that have an kit ethos boro across vape x dovpo

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